A limited capacity for microglial repopulation in the adult brain
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چکیده
منابع مشابه
Microglial repopulation resolves inflammation and promotes brain recovery after injury.
Microglia mediate chronic neuroinflammation following central nervous system (CNS) disease or injury, and in doing so, damage the local brain environment by impairing recovery and contributing to disease processes. Microglia are critically dependent on signaling through the colony-stimulating factor 1 receptor (CSF1R) and can be eliminated via administration of CSF1R inhibitors. Resolving chron...
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ژورنال
عنوان ژورنال: Glia
سال: 2018
ISSN: 0894-1491,1098-1136
DOI: 10.1002/glia.23477